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L7418 Sigma

LAAM hydrochloride

≥98% (HPLC), solid

Synonym: α-1-Acetylmethadol hydrochloride, (αS)-β-[(2S)-2-(Dimethylamino)propyl]-α-ethyl-β-phenyl-benzeneethanol acetate (ester) hydrochloride hydrochloride, Levomethadyl acetate hydrochloride, MK-790 hydrochloride, ORLAAM hydrochloride

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids - Opiod Agonists, Excitatory Amino Acids - Opiod Antagonists,
InChI Key   UXBPQRGCVJOTNT-COBSGTNCSA-N
assay   ≥98% (HPLC)
form   solid
drug control   USDEA Schedule II; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
color   white
solubility   H2O: >5 mg/mL
storage temp.   2-8°C

Description

Other Notes

DEA Schedule II

Biochem/physiol Actions

LAAM hydrochloride is μ opioid receptor agonist. LAAM hydrochloride is a DEA-controlled substance, which has a slow onset, but a long duration of action. LAAM is a useful tool for studying opiate tolerance and cross-reactivity with other μ opioid receptor agonists.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
3
RTECS 
MJ3680000

Documents

Certificate of Analysis


Milli-Q® Water Purification Solutions
Protocols & Articles

Articles

Opioid Receptors

Opioid receptors are distributed widely in brain and found in spinal cord and peripheral sensory and autonomic nerves. There are three well-characterized members of the opioid receptor family, design...
Keywords: Analgesics, Atomic absorption spectroscopy, Gastrointestinal, Gene expression, Ligands, Respiratory, Transduction

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Peer-Reviewed Papers
15

References

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