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M0763 Sigma-Aldrich

Metoclopramide hydrochloride

solid

  • CAS Number 7232-21-5

  • Empirical Formula (Hill Notation) C14H22ClN3O2 · HCl

  • Molecular Weight 336.26

  •  EC Number 230-634-5

  •  MDL number MFCD00058011

  •  PubChem Substance ID 24277919

  •  NACRES NA.77

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Properties

Related Categories Antagonists - Dopaminergics, Approved Therapeutics/Drug Candidates, Baxter, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
Quality Level   100
form   solid
color   white
solubility   H2O: soluble
originator   Baxter
SMILES string   Cl.CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC
InChI   1S/C14H22ClN3O2.ClH/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3;/h8-9H,4-7,16H2,1-3H3,(H,17,19);1H
InChI key   RVFUNJWWXKCWNS-UHFFFAOYSA-N
Gene Information   human ... DRD2(1813), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360)

Description

Packaging

10, 25, 100 g in poly bottle

Biochem/physiol Actions

D2 antagonist; 5-HT3 antagonist; antipsychotic; anti-emetic.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Baxter. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
BZ3325000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Discover Bioactive Small Molecules for Neuroscience

The nervous system, comprised of the brain and spinal cord (central nervous system, or CNS) and network of nerves that connects the CNS to the rest of the body (peripheral nervous system, or PNS) is ...
Keywords: Bioactive small molecules, Central Nervous System, Diseases, Metabolism, Neurodegenerative Diseases, Neuroscience, Neurotransmission, Neurotransmitters

Peer-Reviewed Papers
15

References

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