• USA Home
  • M7065 - MK-912 hydrochloride hydrate

EMAIL THIS PAGE TO A FRIEND
M7065 Sigma-Aldrich

MK-912 hydrochloride hydrate

≥98% (HPLC)

Synonym: (2S-trans)-1,3,4,5′,6,6′,7,12b-Octahydro-1′,3′-dimethyl-spiro[2H-benzofuro[2,3-a]quinolizine-2,4′(1’H)-pyrimidin]-2′(3’H)-one hydrochloride hydrate, L-657,743

  • CAS Number 111466-41-2 (free base)

  • Empirical Formula (Hill Notation) C20H25N3O2 · xHCl · yH2O

  • Molecular Weight 339.43 (anhydrous free base basis)

  •  PubChem Substance ID 24278567

Purchase

Properties

Related Categories Adrenergics, Antagonists- Adrenergics, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
InChI Key   WVVGVFGUHPXSJZ-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   H2O: soluble 16 mg/mL
originator   Merck & Co., Inc., Kenilworth, NJ
Gene Information   human ... ADRB2(154)

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

Selective α2-adrenoceptor antagonist

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the α2-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Merck & Co., Inc., Kenilworth, NJ. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

Material is hygroscopic.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis


Making Headway

Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?