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N4267 Sigma-Aldrich

Neurokinin A

≥97% (HPLC)

Synonym: α-Neurokinin, Neuromedin L, Substance K

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Properties

Related Categories Agonist, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators,
InChI Key   HEAUFJZALFKPBA-UHFFFAOYSA-N
assay   ≥97% (HPLC)
composition   Peptide content, ≥70%
storage temp.   −20°C
Gene Information   human ... TAC1(6863)

Description

Amino Acid Sequence

His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2

General description

Neurokinin A is an 11 amino acid peptide. It is a member of tachykinin family, which includes neurokinin A, neurokinin B, neuropeptide K, neuropeptide Y and hemokinin-1. The gene encoding neurokinin A is localized on human chromosome 7q21.3.

Biochem/physiol Actions

Neurokinin A improves the multiplication and paracrine ability of stem cells acquired from adipose in vitro. It participates in the movement of several organ tracts, triggers glandular secretion and controls autonomic reflexes. Neurokinin A plays an important role in neuroimmune and systemic autoimmune/inflammatory conditions like multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease and also in infections and cancer.

Other Notes

Lyophilized from 0.1% TFA in H2O

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin


Making Headway

Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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