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N5537 Sigma-Aldrich

NDNI hydriodide

solid, (The product is pure based on CHN, NMR, MS)

Synonym: N-n-Decylnicotinium iodide hydriodide

  • Empirical Formula (Hill Notation) C20H36I2N2

  • Molecular Weight 558.32

  •  MDL number MFCD08276923

  •  PubChem Substance ID 24724552

  •  NACRES NA.77

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Properties

Related Categories Antagonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
assay   (The product is pure based on CHN, NMR, MS)
form   solid
storage condition   protect from light
color   light yellow
solubility   H2O: ~15 mg/mL
SMILES string   [I-].I[H].CCCCCCCCCC[n+]1cccc(c1)[C@@H]2CCCN2C
InChI   1S/C20H35N2.2HI/c1-3-4-5-6-7-8-9-10-16-22-17-11-13-19(18-22)20-14-12-15-21(20)2;;/h11,13,17-18,20H,3-10,12,14-16H2,1-2H3;2*1H/q+1;;/p-1/t20-;;/m0../s1
InChI key   NNVBWSUAQNYTGZ-FJSYBICCSA-M

Description

Biochem/physiol Actions

Highly selective α4β2 nicotinic receptor antagonist

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Acetylcholine Receptors (Nicotinic)

Nicotinic acetylcholine receptors (nAChRs) constitute a family of ligand-gated channels, originally classified on the basis of their activation by the alkaloid nicotine, with acetylcholine (ACh) bein...
Keywords: Analgesics, Diseases, Dopamine agents, Gene expression, Genetic, Inflammation, Ligands, Microscopy, Neurotransmission, Neurotransmitters, Scanning electron microscopy, Schizophrenia, Tissue microarrays, Transduction

Peer-Reviewed Papers
15

References

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