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P0018 Sigma

Pomalidomide

≥98% (HPLC)

Synonym: 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline, 3-amino-N-(2,6-dioxo-3-piperidyl)phthalamide, 4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione, Actimid, CC-4047, IMiD 3

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Properties

Related Categories Angiogenesis Regulators, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   UVSMNLNDYGZFPF-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   powder
color   yellow
solubility   DMSO: ≥14 mg/mL
storage temp.   2-8°C

Description

Biochem/physiol Actions

Pomalidomide is a second generation immunomodulator, TNF-α inhibitor, and thalidomide analog.

Packaging

5, 25 mg in glass bottle

Features and Benefits

This compound is featured on the Cytokine Receptors (Tumor Necrosis Receptor Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

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Milli-Q® Water Purification Solutions
Protocols & Articles

Articles

Cytokine Receptors (Tumor Necrosis Receptor Family)

The cytokines and receptors of the Tumor Necrosis Factor (TNF) superfamily serve as an intercellular communication network integrating cellular responses in vertebrates. TNF receptors activate signal...
Keywords: Angiogenesis, Anti-inflammatory agents, Apoptosis, Calcification, Cancer, Cell proliferation, Diseases, Gene expression, Growth factors, Inflammation, Ligands, Transcription, Transduction

Peer-Reviewed Papers
15

References

Related Products

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Product #

Description

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901494 N-Methylated pomalidomide, ≥98%
901495 Pomalidomide-PEG3-NH2 hydrochloride, ≥95%
901496 Pomalidomide-C6-CO2H, ≥98%
901500 Pomalidomide-C3-CO2H, ≥95%
901504 Pomalidomide-PEG3-CO2H, ≥95%
901516 Pomalidomide-PEG1-NH2 hydrochloride, ≥95%
901513 Pomalidomide-PEG2-NH2 hydrochloride, ≥95%
901523 Pomalidomide-PEG1-Alkyne, ≥98%
901531 Pomalidomide-PEG3-Alkyne, ≥98%
901529 Pomalidomide-PEG2-Alkyne, ≥95%
901527 Pomalidomide-PEG1-CO2H, ≥95%
901526 Pomalidomide-PEG2-CO2H, ≥98%
901525 Pomalidomide-C9-CO2H, ≥95%
901558 Lenalidomide, ≥95%
901835 Pomalidomide-PEG6-Alkyne
901834 Pomalidomide-PEG5-Alkyne, ≥95%
901833 Pomalidomide-PEG4-Alkyne
901828 Pomalidomide-PEG5-CO2H, ≥98%
901824 Pomalidomide-PEG4-CO2H

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