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P1431 Sigma-Aldrich

Calmodulin from bovine testes

BioUltra, ≥98% (SDS-PAGE), lyophilized powder

Synonym: CaM, Phosphodiesterase 3′:5′-cyclic nucleotide activator

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Properties

Related Categories Application Index, Biochemicals and Reagents, Calcium-associated Proteins, Cell Biology, Cell Signaling Enzymes,
Quality Level   200
biological source   bovine testis
product line   BioUltra
assay   ≥98% (SDS-PAGE)
form   lyophilized powder
application(s)   cell analysis: suitable
  ligand binding assay: suitable
impurities   salt, essentially free
storage temp.   −20°C
Gene Information   cow ... CALM3(520277)

Description

Application

Calmodulin from bovine testes has been shown to activate a plasma membrane (Ca2+Mg2+)-ATPase in porcine aortic endothelial cells.

Biochem/physiol Actions

Ca2+ binding protein that is required for activation of cyclic nucleotide-dependent phosphodiesterase. It is also a cofactor/activator of nitric oxide synthase, calcineurin, and many kinases including ATPase, myosin light chain kinase, and CAM kinase I, II, and III. It mediates ryanodine receptor activation by cyclic ADP ribose and is involved in intracellular Ca2+ homeostasis.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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