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P1639 Sigma-Aldrich

Patulin

≥98.0% (HPLC)

Synonym: 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one

  • CAS Number 149-29-1

  • Empirical Formula (Hill Notation) C7H6O4

  • Molecular Weight 154.12

  •  Beilstein/REAXYS Number 149675

  •  EC Number 205-735-2

  •  MDL number MFCD00005858

  •  PubChem Substance ID 24898227

  •  NACRES NA.85

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics N-S, Biochemicals and Reagents
Quality Level   300
assay   ≥98.0% (HPLC)
solubility   water: 9-11 mg/mL
Mode of action   cell membrane | interferes
antibiotic activity spectrum   fungi
storage temp.   −20°C
SMILES string   OC1OCC=C2OC(=O)C=C12
InChI   1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2
InChI key   ZRWPUFFVAOMMNM-UHFFFAOYSA-N

Description

Application

Patulin is a mycotoxin produced by a variety of molds, such as, Aspergillus and Penicillium. It is commonly found in apples. It is used as an inhibitor of potassium uptake and as an inducer of ion flux across cell membranes, potentially involving Na+-K+ dependent ATPase and to induce intra- and intermolecular protein crosslinking. It is used to study patulin contamination of bottled wine, DNA-damaging activity of patulin in Escherichia coli, and molecular cloning and functional characterization of two CYP619 cytochrome P450s involved in biosynthesis of patulin in Aspergillus clavatus.

Packaging

5, 10, 25 mg in glass bottle

Biochem/physiol Actions

Patulin is genotoxic and may be carcinogenic.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 3462 6.1 / PGII
WGK Germany 
WGK 3
RTECS 
LV2625000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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