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P2870 Sigma

Pristane

synthetic, ≥98% (GC)

Synonym: 2,6,10,14-Tetramethylpentadecane

  • CAS Number 1921-70-6

  • Linear Formula (CH3)2CH(CH2)3CH(CH3)(CH2)3CH(CH3)(CH2)3CH(CH3)2

  • Molecular Weight 268.52

  •  Beilstein Registry Number 1720538

  •  EC Number 217-650-8

  •  MDL number MFCD00008952

  •  PubChem Substance ID 24898367

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Properties

Related Categories Adjuvant Reagents, Adjuvant emulsions, Antibodies, Antibody Purification and Characterization, Cancer Research,
biological source   synthetic
InChI Key   XOJVVFBFDXDTEG-UHFFFAOYSA-N
assay   ≥98% (GC)
refractive index   n20/D 1.438(lit.)
bp   68 °C/0.001 mmHg(lit.)
density   0.783 g/mL at 20 °C(lit.)

Description

Packaging

100, 250, 500 mL in glass bottle

Application

Pristane has been used as an inflammation-inducing agent, leading to myeloma development in BALB/c strain mice. It has been used as a rheumatoid arthritis-inducing agent in rats.

Biochem/physiol Actions

Pristane is a hydrocarbon oil adjuvant widely used to induce tumorigenesis in mice and arthritis and lupus nephritis in rats. It works as a adjuvant for monoclonal antibody generation in mouse ascites.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
RZ1880000
Flash Point(F) 
>230 °F
Flash Point(C) 
>110 °C

Bulk Chemicals

Cell Culture Guide
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
Vicki Caligur
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Biofiles, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Events, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Sequences, Transcription, Type, transformation

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Bio Brief: Pristane [VIDEO]

Sigma has developed a synthetic alternative to shark-derived pristane. Originally, pristane was isolated from the basking shark. When the basking shark became endangered, Sigma began offering a uniqu...
Keywords: Chromatography, Diseases, Gas chromatography

Cell Culture Troubleshooting Guide

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Peer-Reviewed Papers
15

References

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