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P5669 Sigma-Aldrich

Pyridoxine

≥98%

Synonym: Pyridoxol, Vitamin B6

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Properties

Related Categories Allium cepa (Onion), Biochemicals and Reagents, Cell Biology, Hordeum vulgare (Barley), Nutrition Research,
Quality Level   100
assay   ≥98%
form   powder
application(s)   HPLC: suitable
color   white to off-white
mp   159-162 °C (lit.)
SMILES string   Cc1ncc(CO)c(CO)c1O
InChI   1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3
InChI key   LXNHXLLTXMVWPM-UHFFFAOYSA-N
Gene Information   human ... CYP1A2(1544)

Description

General description

Pyridoxine (vitamin B6) is a form of vitamin B6. Other forms include the aldehyde pyridoxal and the amide pyridoxamine. It is an important cofactor for metabolism.

Vitamin B group are water-soluble and exists in six forms which includes the pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phospate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. Vitamin B6 is distributed in nuts, whole grains and animal meat.

Application

Pyridoxine has been used as a component of:
• artificial diet for sugarcane aphid pest
• modified Strullu and Romand (MSR) medium for carrot root organ culture
• Luria broth for E coli cultures

Pyridoxine is used in cell culture and other applications as a precursor to pyridoxal phosphate. It has been used as a standard in RP-HPLC (reversed phase high performance liquid chromatography) method. Pyridoxine has been used as a diet supplement to study lipid profile in rats.

Biochem/physiol Actions

Pyridoxine plays a key role in cell maintenance and amino acid metabolism. Deficiency of vitamin B6 leads to anemia especially in pregnant women and seizures in newborns. It serves as cofactor for heme biosynthesis during δ-amino levulinic acid formation, γ-aminobutyric acid (GABA) transaminase and glutamic acid decarboxylase. Vitamin B6 also helps in reactive oxygen species (ROS) scavenging and helps plants in overcoming the abiotic and biotic stress.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

HILIC Analysis of Polar Vitamins on Ascentis® Express OH5

From our library of Articles, Sigma-Aldrich presents HILIC Analysis of Polar Vitamins on Ascentis® Express OH5
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Vitamins, Water Soluble on Discovery® C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Vitamins, Water Soluble on Discovery® C18
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Vitamins, Water Soluble, on Ascentis® RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Vitamins, Water Soluble, on Ascentis® RP-Amide
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Vitamins, Water Soluble, on Discovery® C8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Vitamins, Water Soluble, on Discovery® C8
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Vitamins, Water Soluble, on Discovery® RP-Amide C16

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Vitamins, Water Soluble, on Discovery® RP-Amide C16
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Water Soluble Vitamins on Ascentis® RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Water Soluble Vitamins on Ascentis® RP-Amide
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of an Energy Drink on Ascentis® Express HILIC, 10 cm (UV Detection)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of an Energy Drink on Ascentis® Express HILIC, 10 cm (UV Detection)
Keywords: Chromatography, High performance liquid chromatography

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

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Keywords: Biochemistry, Biological Buffers, Buffers, Detergents

Peer-Reviewed Papers
15

References

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