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PZ0001 Sigma

Atorvastatin calcium salt trihydrate

≥98% (HPLC)

  • CAS Number 134523-03-8 (anhydrous)

  • Empirical Formula (Hill Notation) C33H34FN2O5 · 0.5 Ca · 1.5 H2O

  • Molecular Weight 604.69

  •  PubChem Substance ID 329823670



Related Categories AN-AZ, Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
assay   ≥98% (HPLC)
form   white powder
storage condition   protect from light
solubility   DMSO: ≥10 mg/mL
originator   Pfizer
storage temp.   room temp


Other Notes

This compound was developed by Pfizer for Lipid Signaling research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


5, 25 mg in glass bottle

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC


Atorvastatin calcium salt trihydrate has been used in the enzymatic method to measure mevalonic acid in serum.

Biochem/physiol Actions

Atorvastatin calcium salt trihydrate is a specific inhibitor of HMG-CoA reductase. HMG-CoA reductase is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. Atorvastatin is used in the treatment of hypercholesterolemia.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®Pfizer), a collection of 90 Pfizer-developed drugs and research tools. Click here to learn more.

General description

Atorvastatin calcium salt trihydrate is an anti-hyperlipoproteinemic and a synthetic cholesterol-reducing agent. It is a crystalline powder.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis

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Protocols & Articles


Antilipemic Agents

Download BioFiles v7 n5 (3.18 Mb PDF) Back to Pharmaceutical Drugs and Drug Candidates homepage
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BioFiles v7 n5, 2012, 21–24
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Discover Bioactive Small Molecules for Lipid Signaling Research

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