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S5068 Sigma

Salmeterol xinafoate

≥98% (HPLC), solid

Synonym: (±) 4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]m-ethyl]-1,3-benzenedimethanol xinafoate, GR 33343X xinafoate

  • CAS Number 94749-08-3

  • Empirical Formula (Hill Notation) C25H37NO4 · C11H8O3

  • Molecular Weight 603.75

  •  MDL number MFCD00897708

  •  PubChem Substance ID 24278713

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Properties

Related Categories Adrenergics, Adrenergics - Agonists, Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index,
InChI Key   XTZNCVSCVHTPAI-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   solid
color   white
solubility   H2O: slightly soluble
  ethanol: slightly soluble
  methanol: freely soluble
originator   GlaxoSmithKline
Gene Information   human ... ADRB2(154)

Description

Biochem/physiol Actions

β2-adrenoceptor agonist.

Salmeterol xinafoate is a β2 adrenoceptor agonist with longer lasting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles, stabilizes mast cells and regulates the release of histamine. Salmetrol is particularly effective in treatment of mild asthma, chronic obstructive pulmonary disorder.5,6

Packaging

10, 50 mg in glass insert

Application

Salmeterol xinafoate was used as conjugate with human serum albumin to study the immune responses in rabbits.7

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin


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