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S8692 Sigma

Sulprostone

≥95% (HPLC), oil

Synonym: (5Z,11α,13E,15R)--11,15-Dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranorprosta-5,13-dienoic acid methane sulfonamide, CP-34089, SHB-286, ZK-57671

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Properties

Related Categories Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology,
InChI Key   UQZVCDCIMBLVNR-TWYODKAFSA-N
assay   ≥95% (HPLC)
form   oil
color   colorless to yellow-brown
solubility   DMSO: >10 mg/mL
shipped in   wet ice
storage temp.   −20°C

Description

Biochem/physiol Actions

Selective EP3 prostanoid receptor agonist.

Sulprostone is an analog of prostaglandin E2 (PGE2)1 and antagonizes vasopressin-induced antidiuretic responses in cells from rat renal inner medullae by a mechanism that involves activation of Rho.2

Packaging

1, 5 mg in glass bottle

Application

Human chondrocytes3 and mouse adrenal chromaffin cells4 were treated with sulprostone to study the biological effects of PGE2.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
MJ8810000

Webinar - Hydrogels
Protocols & Articles
Peer-Reviewed Papers
15

References

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