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S9132 Sigma-Aldrich

Spiramycin

Synonym: Formacidine

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Properties

Related Categories Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Mechanism of Action,
InChI Key   ACTOXUHEUCPTEW-JMRHEKERSA-N
form   powder
optical activity   [α]/D -85 to -80° in water (Specific rotation (dry basis))
potency   ≥4100 I.U. per mg (dry basis)
color   white to light yellow
solubility   methanol: soluble
cation traces   heavy metals: ≤20 ppm
Mode of action   protein synthesis | interferes
antibiotic activity spectrum   Gram-positive bacteria
storage temp.   2-8°C

Description

General description

Chemical structure: macrolide

Application

Spiramycin is a macrolide antibiotic that is commonly used to treat infections of soft tissues. It has been used to treat bronchopulmonary infections in adults and has been used to study septicemia in mice .

Packaging

1, 5 g in poly bottle

Biochem/physiol Actions

Spiramycin is a 16-membered ring macrolide antibiotic from Streptomyces ambofaciens. It inhibits bacterial protein synthesis at the level of peptidy-tRNA dissociation from ribosomes. It is mainly used against Gram-positive bacteria.

Quality

A mixture of Spiramycin I, II and III.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
WG9400000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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