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SML0829 Sigma

Dermorphin trifluoroacetate salt

≥98% (HPLC)

  • CAS Number 77614-16-5 (free base)

  • Empirical Formula (Hill Notation) C40H50N8O10 · xC2HF3O2

  • Molecular Weight 802.87 (free base basis)

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, D-DIF,
assay   ≥98% (HPLC)
form   powder
color   white to off-white
shipped in   wet ice
storage temp.   −20°C

Description

Amino Acid Sequence

Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2 trifluoroacetate salt

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

Dermorphin is a natural opioid originally isolated from the skin of South American frogs Dermophin has high selectivity as a μ-Opioid receptor (MOR) agonist and is 30–40 times more potent than morphine.

Features and Benefits

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

General description

Dermorphin is an opioid receptor that has a D-amino acid residue in their sequence. This is liberated from a biosynthetic precursor having several copies of dermorphin with the L-isomer only.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis


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Making Headway
Protocols & Articles

Articles

LC/MS (TOF) Analysis of Dermorphin on Ascentis® Express F5

From our library of Articles, Sigma-Aldrich presents LC/MS (TOF) Analysis of Dermorphin on Ascentis® Express F5
Keywords: Chromatography, High performance liquid chromatography, Mass spectrometry, Separation, Solid phase extractions

Opioid Receptors

Opioid receptors are distributed widely in brain and found in spinal cord and peripheral sensory and autonomic nerves. There are three well-characterized members of the opioid receptor family, design...
Keywords: Analgesics, Atomic absorption spectroscopy, Gastrointestinal, Gene expression, Ligands, Respiratory, Transduction

Peer-Reviewed Papers
15

References

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