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SML1654 Sigma

R-Ketorolac

≥95% (HPLC)

Synonym: (+)-Ketorolac, (1R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;, (R)-(+)-ketorolac, (R)-Ketorolac

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, G Protein Function,
InChI Key   OZWKMVRBQXNZKK-LLVKDONJSA-N
assay   ≥95% (HPLC)
form   powder
optical activity   [α]/D +162 to +178°, c = 1 in methanol
color   white to beige
solubility   DMSO: 25 mg/mL, clear
storage temp.   −20°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

R-Ketorolac is potent and selective Rho-family GTPases Cdc42 (cell division control protein 42) and Rac1 (Ras-related C3 botulinum toxin substrate 1) allosteric inhibitor that modulates downstream GTPase-dependent physiologic responses critical to tumor metastasis. R-ketorolac significantly inhibits ovarian cancer cell adhesion, migration, and invasion.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis


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Peer-Reviewed Papers
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