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SML2276 Sigma-Aldrich

TH-263

≥98% (HPLC)

Synonym: 4-[(Phenylamino)sulfonyl]-N-(phenylmethyl)benzamide, N-Benzyl-4-(benzylsulfamoyl)benzamide

  • CAS Number 1004044-80-7

  • Empirical Formula (Hill Notation) C20H18N2O3S

  • Molecular Weight 366.43

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, T
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 2 mg/mL, clear
storage temp.   2-8°C
SMILES string   O=C(C1=CC=C(C=C1)S(NC2=CC=CC=C2)(=O)=O)NCC3=CC=CC=C3

Description

Biochem/physiol Actions

TH263 is an inactive analog control for the type III allosteric LIM-kinase (LIMK) inhibitors TH-257, TH-255 and TH-251. For characterization details of the active probe, TH-257, please visit the TH-257 probe summary on the Structural Genomics Consortium (SGC) website.

TH-257, the active probe, is available from Sigma. To learn more about and purchase TH-257, click here.

To learn about other SGC chemical probes, visit sigma.com/sgc

Features and Benefits

TH-236 is a negative control for TH-257, a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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