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T6950 Sigma

Tizanidine hydrochloride

≥98% (HPLC), powder

Synonym: 5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine hydrochloride

  • CAS Number 64461-82-1

  • Empirical Formula (Hill Notation) C9H9Cl2N5S

  • Molecular Weight 290.17

  •  MDL number MFCD00798231

  •  PubChem Substance ID 24724634

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Description

Biochem/physiol Actions

α2-adrenoceptor agonist.

Tizanidine hydrochloride is known to function as a skeletal muscle relaxant that acts centrally. Furthermore, this relaxant functions at spinal and supraspinal levels to block excitatory interneurons. This drug is used for the symptomatic relief of spasticity and painful muscle spasms.

Packaging

10, 50 mg in glass bottle

Preparation Note

Tizanidine hydrochloride is soluble in water at a concentration that is greater than 20 mg/ml.

Application

Tizanidine hydrochloride has been used for developing spectrophotometric methods for the validation of skeletal muscle relaxants.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by Acorda Therapeutics. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
DK9910000

Documents

Certificate of Analysis


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Peer-Reviewed Papers
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References

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