EMAIL THIS PAGE TO A FRIEND
U3750 Sigma-Aldrich

Uridine

≥99%

Synonym: 1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside

  • CAS Number 58-96-8

  • Empirical Formula (Hill Notation) C9H12N2O6

  • Molecular Weight 244.20

  •  Beilstein/REAXYS Number 754902

  •  EC Number 200-407-5

  •  MDL number MFCD00006526

  •  PubChem Substance ID 24900640

  •  NACRES NA.51

Purchase

Properties

Related Categories Biochemicals and Reagents, Cell Biology, Nucleosides, Nucleosides, Nucleotides, Oligonucleotides, Nutrition Research,
Quality Level   200
biological source   synthetic (organic)
assay   ≥99%
form   powder
mp   163-167 °C (lit.)
solubility   H2O: 50 mg/mL, clear, colorless
SMILES string   OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
InChI   1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChI key   DRTQHJPVMGBUCF-XVFCMESISA-N
Gene Information   mouse ... Uck1(22245)

Description

General description

Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is synthesized in living organisms by de novo and salvage pathways.

Application

Uridine has been used:
• as a component of hippocampal neuron medium for culture of primary hippocampal neuron cells
• in uridine rescue experiments in mouse embryonic fibroblasts and human breast cancer cells
• in chase sequencing experiments

Packaging

1, 25, 100 g in poly bottle

Biochem/physiol Actions

Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine are implicated in insulin resistance.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles

Articles

HPLC Analysis of Nucleosides on Ascentis® Phenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Nucleosides on Ascentis® Phenyl
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Nucleosides on Ascentis® Si (Silica)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Nucleosides on Ascentis® Si (Silica)
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Ribonucleosides on Ascentis® Si

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Ribonucleosides on Ascentis® Si
Keywords: Chromatography, High performance liquid chromatography

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

UHPLC Analysis of Nucleosides on Purospher® STAR RP-18 endcapped

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Nucleosides on Purospher® STAR RP-18 endcapped
Keywords: Antibiotics, Antivirals, Fungicides, Genetic, Herbicides, High performance liquid chromatography, Industries, Insecticides

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?