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V4765 Sigma

Valnoctamide

≥98% (NMR)

Synonym: 2-ethyl-3-methyl-pentanamide, Axiquel, Nirvanil

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, V
InChI Key   QRCJOCOSPZMDJY-UHFFFAOYSA-N
assay   ≥98% (NMR)
form   powder
storage condition   desiccated
color   white to off-white
solubility   DMSO: 20 mg/mL, clear
storage temp.   room temp

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

Valproic acid (VPA) and derivatives such as valpromide and valnoctamide are anti-convulsant, mood stabilizing drugs, believed to function as indirect GABA agonists by inhibiting the transamination of GABA.

Features and Benefits

This compound is featured on the Glutamate/GABA Synthesis and Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
YV5950000

Documents

Certificate of Analysis


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Making Headway
Protocols & Articles

Articles

Glutamate/GABA Synthesis and Metabolism

Glutamine is a common precursor for the biosynthesis of both glutamate and GABA. Glutamine can be transported in and out of neurons and astrocytes utilizing different glutamine carriers. Three such c...
Keywords: Anticonvulsants, Catalysis, Citric Acid Cycle, Gene expression, Metabolism, Neurotransmitters, Nuclear magnetic resonance spectroscopy, Schizophrenia, Spectroscopy, Transaminations

Peer-Reviewed Papers
15

References

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