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W3020 Sigma-Aldrich

WKYMVdM trifluoroacetate salt

≥98% (HPLC), powder

Synonym: Trp-Lys-Tyr-Met-Val-D-Met NH2 trifluoroacetate salt trifluoroacetate salt

  • Empirical Formula (Hill Notation) C41H61N9O7S2 · xC2HF3O2

  • Molecular Weight 856.11 (free base basis)

  •  MDL number MFCD09039057

  •  PubChem Substance ID 329830554

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Immune Cell Signaling and Blood,
InChI Key   MYVYQWVNXDVTBW-HQORXVKSSA-N
assay   ≥98% (HPLC)
form   powder
color   white to off-white
solubility   H2O: >2 mg/mL
storage temp.   −20°C

Description

Amino Acid Sequence

Trp-Lys-Tyr-Met-Val-D-Met NH2

Packaging

1 mg in glass bottle

Biochem/physiol Actions

WKYMVm is a very potent agonist of formyl peptide receptor members FPR1/FPR2 (EC50 1 nM) and FPRL1/FPRL2 (75 pM and 3 nM, respectively). WKYMVm stimulation of leukocytes has been shown to elevate intracellular calcium, induce chemotaxis, superoxide generation, cell killing and phagocytosis.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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