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Z0877 Sigma

Zotepine

Synonym: 2-[(8-chlorodibenzo[b,f]-thiepin-10-yl)oxy]-N,N-dimethylethanamine

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Astellas, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
InChI Key   HDOZVRUNCMBHFH-UHFFFAOYSA-N
assay   >98% (HPLC)
form   powder
color   white to off-white
solubility   DMSO: ≥20 mg/mL
originator   Astellas
storage temp.   room temp

Description

Biochem/physiol Actions

Zotepine is an atypical antipsychotic.

Packaging

10, 50 mg in glass bottle

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Astellas. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. Z0877.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis


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Protocols & Articles

Articles

Dopamine Receptors

Dopamine receptors were initially differentiated into two major types based on the ability of dopamine to stimulate (D1) or inhibit (D2) adenylyl cyclase activity and produce the second-messenger mol...
Keywords: Atomic absorption spectroscopy, Dopamine agents, Gene expression, Genetic, Genetics, Ligands, Methylations, Parkinson Disease, Schizophrenia, Transduction

Serotonin Receptors

Serotonin (5-hydroxytryptamine, 5-HT) is widely distributed throughout the mammalian body, being synthesized from L-tryptophan in enterochromaffin cells of the gastro-intestinal tract as well as in s...
Keywords: Active transport, Atomic absorption spectroscopy, Cancer, Clinical, Gene expression, Ligands, Neurotransmitters, Obesity, Polymorphisms, Schizophrenia, Transduction

Peer-Reviewed Papers
15

References

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