EMAIL THIS PAGE TO A FRIEND
Z0877 Sigma-Aldrich

Zotepine

Synonym: 2-[(8-chlorodibenzo[b,f]-thiepin-10-yl)oxy]-N,N-dimethylethanamine

  • CAS Number 26615-21-4

  • Empirical Formula (Hill Notation) C18H18ClNOS

  • Molecular Weight 331.86

  •  MDL number MFCD00868143

  •  PubChem Substance ID 329831602

  •  NACRES NA.77

Purchase

Properties

Related Categories Approved Therapeutics/Drug Candidates, Astellas, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
Quality Level   100
assay   >98% (HPLC)
form   powder
color   white to off-white
solubility   DMSO: ≥20 mg/mL
originator   Astellas
storage temp.   room temp
SMILES string   CN(C)CCOC1=Cc2ccccc2Sc3ccc(Cl)cc13
InChI   1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3
InChI key   HDOZVRUNCMBHFH-UHFFFAOYSA-N

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Zotepine is an atypical antipsychotic.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Astellas. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. Z0877.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Articles

Dopamine Receptors

Dopamine receptors were initially differentiated into two major types based on the ability of dopamine to stimulate (D1) or inhibit (D2) adenylyl cyclase activity and produce the second-messenger mol...
Keywords: Atomic absorption spectroscopy, Dopamine agents, Gene expression, Genetic, Genetics, Ligands, Methylations, Parkinson Disease, Schizophrenia, Transduction

Serotonin Receptors

Serotonin (5-hydroxytryptamine, 5-HT) is widely distributed throughout the mammalian body, being synthesized from L-tryptophan in enterochromaffin cells of the gastro-intestinal tract as well as in s...
Keywords: Active transport, Atomic absorption spectroscopy, Cancer, Clinical, Gene expression, Ligands, Neurotransmitters, Obesity, Polymorphisms, Schizophrenia, Transduction

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?