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Z2777 Sigma

Ziprasidone hydrochloride monohydrate

≥98% (HPLC), solid

Synonym: 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride monohydrate, CP-88059, Geodon

  • CAS Number 138982-67-9

  • Empirical Formula (Hill Notation) C21H21ClN4OS · HCl · H2O

  • Molecular Weight 467.41

  •  MDL number MFCD00921885

  •  PubChem Substance ID 329831608

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Description

Biochem/physiol Actions

Ziprasidone is an atypical antipsychotic; FDA approved for the treatment of schizophrenia.

Packaging

5, 25 mg in glass bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the α1-Adrenoceptors, Dopamine Receptors and Histamine Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Central nervous system, Liver
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis


Discover your Target

Making Headway
Protocols & Articles

Articles

Dopamine Receptors

Dopamine receptors were initially differentiated into two major types based on the ability of dopamine to stimulate (D1) or inhibit (D2) adenylyl cyclase activity and produce the second-messenger mol...
Keywords: Atomic absorption spectroscopy, Dopamine agents, Gene expression, Genetic, Genetics, Ligands, Methylations, Parkinson Disease, Schizophrenia, Transduction

Histamine Receptors

The biogenic amine histamine plays an important role in a variety of pathophysiological conditions. In peripheral tissues, histamine is mainly stored in mast cells and basophils. In allergic conditio...
Keywords: Alzheimer Disease, Atomic absorption spectroscopy, Cardiovascular, Clinical, Diseases, Gene expression, Inflammation, Ligands, Neurotransmitters, Obesity, Transduction

Serotonin Receptors

Serotonin (5-hydroxytryptamine, 5-HT) is widely distributed throughout the mammalian body, being synthesized from L-tryptophan in enterochromaffin cells of the gastro-intestinal tract as well as in s...
Keywords: Active transport, Atomic absorption spectroscopy, Cancer, Clinical, Gene expression, Ligands, Neurotransmitters, Obesity, Polymorphisms, Schizophrenia, Transduction

α1-Adrenoceptors

α1-Adrenoceptors are widely distributed, and are activated either by norepinephrine released from sympathetic nerve terminals or by epinephrine released from the adrenal medulla. Receptor activation ...
Keywords: Apoptosis, Atomic absorption spectroscopy, Gene expression, Gluconeogenesis, Transduction

Peer-Reviewed Papers
15

References

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