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Phylloquinone (K1)

analytical standard

Synonym: 2-Methyl-3-phytyl-1,4-naphthoquinone, 3-Phytylmenadione, Phylloquinone, Vitamin K1(20), Vitamin K1

  • CAS Number 84-80-0

  • Empirical Formula (Hill Notation) C31H46O2

  • Molecular Weight 450.70

  •  Beilstein/REAXYS Number 2568816

  •  EC Number 201-564-2

  •  MDL number MFCD00214063

  •  PubChem Substance ID 24871410

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Application Areas and Market Segments, Biochemicals and Reagents,
Quality Level   100
grade   analytical standard
form   neat
feature   standard type fat soluble vitamin
packaging   ampule of 100 mg
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
refractive index   n20/D 1.527 (lit.)
mp   −20 °C (lit.)
density   0.984 g/mL at 25 °C (lit.)
Featured Industry   Cleaning Products
Cosmetics
Food and Beverages
Personal Care
Pharmaceutical (small molecule)
Vitamins, Nutraceuticals, and Natural Products
format   neat
storage temp.   2-8°C
SMILES string   O=C(C1=CC=CC=C21)C(C)=C(C/C=C(CCC[C@@H](CCC[C@H](C)CCCC(C)C)C)\C)C2=O
InChI   1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1
InChI key   MBWXNTAXLNYFJB-NKFFZRIASA-N

Description

General description

Phylloquinone (K1) is a prenylated naphthoquinone. It is a fat soluble vitamin, produced by plants, green algae and some species of cyanobacteria. It functions as a coenzyme and is important for the synthesis of a number of proteins involved in blood clotting and bone metabolism.

Application

Phylloquinone (K1) may be used as an analytical reference standard for the quantification of the analyte in olive oil, chard, human plasma samples, animal and plant food products using reversed-phase high-performance liquid chromatography technique.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
RTECS 
QJ5800000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of Fat Soluble Vitamins on Ascentis® Express RP-Amide, Acetonitrile Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Fat Soluble Vitamins on Ascentis® Express RP-Amide, Acetonitrile Mobile Phase
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Fat Soluble Vitamins on Ascentis® Express RP-Amide, Methanol Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Fat Soluble Vitamins on Ascentis® Express RP-Amide, Methanol Mobile Phase
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Fat-Soluble Vitamins on Ascentis® Express C18, Methanol Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Fat-Soluble Vitamins on Ascentis® Express C18, Methanol Mobile Phase
Keywords: Chromatography, High performance liquid chromatography, Vitamins

UHPLC Analysis of Vitamin K1 and Related Compound on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Vitamin K1 and Related Compound on Ascentis® Express C18
Keywords: Chromatography, Vitamins

UHPLC/MS Analysis of Vitamin K1 and Related Compound on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Vitamin K1 and Related Compound on Ascentis® Express C18
Keywords: Chromatography, Clinical, Mass spectrometry, Vitamins

Peer-Reviewed Papers
15

References

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