EMAIL THIS PAGE TO A FRIEND
1316004 USP

Hydrocortisone

United States Pharmacopeia (USP) Reference Standard

Synonym: 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione, 17-Hydroxycorticosterone, 4-Pregnene-11β,17α,21-triol-3,20-dione, Cortisol, Kendall’s compound F, Reichstein’s substance M

  • CAS Number 50-23-7

  • Empirical Formula (Hill Notation) C21H30O5

  • Molecular Weight 362.46

  •  Beilstein/REAXYS Number 1354819

  •  MDL number MFCD00011654

  •  PubChem Substance ID 329750063

Purchase

Properties

Related Categories Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards G - H More...
grade   pharmaceutical primary standard
form   neat
mfr. no.   USP
mp   211-214 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
SMILES string   [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO
InChI   1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
InChI key   JYGXADMDTFJGBT-VWUMJDOOSA-N
Gene Information   human ... NR3C1(2908)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.

Sales restrictions may apply.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Articles

HPLC Analysis of Cortocisteroids in Urine on Discovery® HS F5 after SPE using Discovery® DSC-CN

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Cortocisteroids in Urine on Discovery® HS F5 after SPE using Discovery® DSC-CN
Keywords: Calorimetry, Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical, Sample preparations, Solid phase extractions

Separation of steroids on Silica gel 60 RP-18

From our library of Articles, Sigma-Aldrich presents Separation of steroids on Silica gel 60 RP-18

TLC Analysis of Steroids on HPTLC Silica Gel 60 F 254

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Steroids on HPTLC Silica Gel 60 F 254
Keywords: Clinical, Thin layer chromatography

TLC Analysis of Steroids on HPTLC Silica gel 60 CN F254s

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Steroids on HPTLC Silica gel 60 CN F254s

TLC Analysis of Steroids on HPTLC Silica gel 60 DIOL F254s

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Steroids on HPTLC Silica gel 60 DIOL F254s

TLC Analysis of Steroids on HPTLC Silica gel 60 RP-18 F254s

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Steroids on HPTLC Silica gel 60 RP-18 F254s
Keywords: Chromatography, Thin layer chromatography

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

PHR1014 Hydrocortisone, Pharmaceutical Secondary Standard; Certified Reference Material

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?