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1356971 USP

Letrozole

United States Pharmacopeia (USP) Reference Standard

Synonym: 4,4′-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile

  • CAS Number 112809-51-5

  • Empirical Formula (Hill Notation) C17H11N5

  • Molecular Weight 285.30

  •  MDL number MFCD00866241

  •  PubChem Substance ID 329750236

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards L - M More...
InChI Key   HPJKCIUCZWXJDR-UHFFFAOYSA-N
Featured Industry   Pharmaceutical (small molecule)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Letrozole is a third generation nonsteroidal aromatase inhibitor. It is a competitive inhibitor of the aromatase enzyme system and thus inhibits the conversion of androgens to estrogens. Letrozole inhibits the aromatase enzyme by competitively binding to the heme of the cytochrome P450 subunit of the enzyme, resulting in a reduction of estrogen biosynthesis in all tissues.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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