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V900742 Sigma-Aldrich

Furazolidone

Vetec, reagent grade

Synonym: 3-(5-Nitrofurfurylideneamino)-2-oxazolidinone

  • CAS Number 67-45-8

  • Empirical Formula (Hill Notation) C8H7N3O5

  • Molecular Weight 225.16

  •  Beilstein/REAXYS Number 8317414

  •  EC Number 200-653-3

  •  MDL number MFCD00010550

  •  PubChem Substance ID 329830114

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Properties

grade   reagent grade
product line   Vetec
solubility   formic acid: 50 mg/mL
antibiotic activity spectrum   Gram-positive bacteria
  parasites
SMILES string   [O-][N+](=O)c1ccc(\C=N\N2CCOC2=O)o1
InChI   1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+
InChI key   PLHJDBGFXBMTGZ-WEVVVXLNSA-N

Description

General description

Furazolidone is a synthetic organic compound that belongs to nitrofurans that are initially derived from furfural. It exhibits antibacterial and antihelmintic properties in humans and animals.

Application

The minimum inhibitory concentration of furazolidone was assessed to study the nonreplicating persistence of M. tuberculosis in aerobic and anaerobic conditions using luminescence-based low-oxygen-recovery assay.

Packaging

10 g in glass bottle

Biochem/physiol Actions

Furazolidone induces interstrand cross-links in subsequent mutation in bacterial cells. It also inhibits mono and diamine oxidase activities in eukaryotes.

Legal Information

Vetec is a trademark of Sigma-Aldrich International GmbH

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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