• USA Home
  • 02615 - (Ethoxycarbonylmethyl)triphenylphosphonium chloride

EMAIL THIS PAGE TO A FRIEND
02615 Sigma-Aldrich

(Ethoxycarbonylmethyl)triphenylphosphonium chloride

technical, ≥90% (AT)

Synonym: (2-Ethoxy-2-oxoethyl)triphenylphosphonium chloride

  • CAS Number 17577-28-5

  • Linear Formula CH3CH2OCOCH2P(Cl)(C6H5)3

  • Molecular Weight 384.84

  •  Beilstein/REAXYS Number 3924139

  •  EC Number 241-548-2

  •  MDL number MFCD00011746

  •  PubChem Substance ID 24845340

  •  NACRES NA.22

Purchase

Properties

Related Categories C-C Bond Formation, Chemical Synthesis, Olefination, Synthetic Reagents, Wittig Reagents More...
grade   technical
assay   ≥90% (AT)
reaction suitability   reaction type: C-C Bond Formation
mp   120-123 °C (dec.)
  120-123 °C (lit.)
storage temp.   2-8°C
SMILES string   [Cl-].CCOC(=O)C[P+](c1ccccc1)(c2ccccc2)c3ccccc3
InChI   1S/C22H22O2P.ClH/c1-2-24-22(23)18-25(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21;/h3-17H,2,18H2,1H3;1H/q+1;/p-1
InChI key   DJGHVEPNEJKZBF-UHFFFAOYSA-M

Description

Application

Reactant for:
• Preparation of disubstituted tetrahydrofurans as selective serotonin re-uptake inhibitors for the treatment of depression
• Ring-opening reactions with Wittig reagents
• Enantioselective total synthesis of the phytotoxic lactone herbarumin III via Keck′s asymmetric allylation and Sharpless epoxidation
• Synthesis of fluorobenzofurans via microwave-assisted tandem intramolecular Wittig and Claisen rearrangement reactions
• Preparation of phosphonium derivatives of coumarin

Other Notes

Starting material for preparing the Wittig-reagent

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?