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101052 Sigma-Aldrich

2,3,4,5,6-Pentafluorobenzyl bromide

99%

Synonym: α-Bromo-2,3,4,5,6-pentafluorotoluene, (Bromomethyl)pentafluorobenzene

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Properties

Related Categories Aryl, Aryl Fluorinated Building Blocks, Building Blocks, C7, Chemical Synthesis,
InChI Key   XDEPVFFKOVDUNO-UHFFFAOYSA-N
assay   99%
refractive index   n20/D 1.471 (lit.)
bp   174-175 °C(lit.)
mp   19-20 °C (lit.)
density   1.728 g/mL at 25 °C (lit.)

Description

Packaging

1, 5, 25 g in glass bottle

Application

Derivatizing agent for GC analysis of polyfunctional thiols.

For the preparation of pentafluorobenzyl esters of organic acids for determination by capillary and GC. Also used to derivatize N-7-substituted guanine adducts of DNA for determination by GC-electron capture-MS.

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3265 8 / PGII
WGK Germany 
3
Flash Point(F) 
181.4 °F
Flash Point(C) 
83 °C

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Protocols & Articles

Articles

DNA Damage and Repair

Damage to cellular DNA is involved in mutagenesis and the development of cancer. The DNA in a human cell undergoes several thousand to a million damaging events per day, generated by both external (e...
Keywords: AGE, Alkylations, Apoptosis, Biochemistry, Cancer, Carcinogens, Catalysis, Clinical, DNA replication, Deaminations, Degradations, Eliminations, Environmental, Enzymology, Gene expression, Genetic, Infrared spectroscopy, Metabolites, Methylations, Mutagens, Oncology, Oxidations, Polymorphisms, Rearrangements, Recombination, Substitutions, Transcription, transformation

Peer-Reviewed Papers
15

References

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