• USA Home
  • 115568 - (S)-(−)-α-Methylbenzylamine

EMAIL THIS PAGE TO A FRIEND
115568 Sigma-Aldrich

(S)-(−)-α-Methylbenzylamine

98%

Synonym: (S)-(−)-1-Phenylethylamine, (S)-(-)-alpha-Methylbenzylamine

  • CAS Number 2627-86-3

  • Linear Formula C6H5CH(CH3)NH2

  • Molecular Weight 121.18

  •  Beilstein/REAXYS Number 2204907

  •  EC Number 220-098-0

  •  MDL number MFCD00064406

  •  PubChem Substance ID 24847225

  •  NACRES NA.22

Purchase

Properties

Related Categories Amines, Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Chiral Resolution Reagents,
vapor pressure   0.5 mmHg ( 20 °C)
InChI Key   RQEUFEKYXDPUSK-ZETCQYMHSA-N
assay   98%
optical activity   [α]20/D −39°, neat
optical purity   ee: 98% (GLC)
refractive index   n20/D 1.526 (lit.)
bp   187 °C (lit.)
density   0.94 g/mL at 25 °C (lit.)
storage temp.   2-8°C

Description

Application

(S)-(-)-α-Methylbenzylamine along with 2-formylphenylboronic acid has been used in a derivatization protocol to analyze the enantiomeric excess of chiral diols.
It can also be used:
• In the diastereoselective synthesis of S-aminonitriles.
• As a chiral auxiliary in the synthesis of (S)-(-)-N-acetylcalycotomine or (R)-(+)-N-acetylcalycotomine.
• As a chiral building block in the asymmetric synthesis of 1-substituted tetrahydro-β-carbolines.

Used in a one-pot, multi-component synthesis of a highly substituted, chiral pyrrole.

Packaging

25, 100 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2922 6.1(8) / PGII
WGK Germany 
1
Flash Point(F) 
158 °F
Flash Point(C) 
70 °C

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles

Articles

HPLC Analysis of α-Methylbenzylamine Enantiomers (DANSYL Derivatives) on Astec® CYCLOBOND® I 2000 DMP

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of α-Methylbenzylamine Enantiomers (DANSYL Derivatives) on Astec® CYCLOBOND® I 2000 DMP
Keywords: Chromatography, High performance liquid chromatography

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?