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119725 Sigma-Aldrich

4′-Piperidinoacetophenone

97%

Synonym: 1-[4-(1-Piperidinyl)]phenyl]ethanone

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Properties

Related Categories Building Blocks, C13, Chemical Synthesis, Heterocyclic Building Blocks, Piperidines More...
InChI Key   JCMZZYSPSGHBNM-UHFFFAOYSA-N
assay   97%
mp   85-87 °C (lit.)

Description

General description

4′-Piperidinoacetophenone undergoes Claisen-Schmidt condensation with substituted benzaldehydes using NaOH-Al2O3 by microwave irradiation to give chalcones. It has antimycobacterial activity.

Application

4′-Piperidinoacetophenone was used as internal standard in the determination of pethidine, a narcotic analgesic drug in body fluids by gas chromatography-tandem mass spectrometry.

Pharmacological activity:
• Selective antimycobacterial activity
• Bronchodilator compound
• Modulation of flagellar motility in Chlamydomonas

Packaging

25 g in poly bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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