• USA Home
  • 125180 - 1-(3-Chlorophenyl)piperazine hydrochloride

EMAIL THIS PAGE TO A FRIEND
125180 Sigma-Aldrich

1-(3-Chlorophenyl)piperazine hydrochloride

99%

Synonym: m-CPP

  • CAS Number 65369-76-8

  • Empirical Formula (Hill Notation) C10H13ClN2 · xHCl

  • Molecular Weight 196.68 (free base basis)

  •  EC Number 265-718-0

  •  MDL number MFCD00039032

  •  PubChem Substance ID 24847652

Purchase

Properties

Related Categories Agonists, Building Blocks, C10, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   MHXPYWFZULXYHT-UHFFFAOYSA-N
assay   99%
mp   210-214 °C (dec.) (lit.)
solubility   methanol: soluble
Gene Information   rat ... Htr1a(24473)

Description

General description

1-(3-Chlorophenyl)piperazine hydrochloride is sold as Ecstasy mimic tablets and is the major metabolite of the antidepressant medications trazodone and nefazodone.

Application

1-(3-Chlorophenyl)piperazine hydrochloride (CPP) has been used in determination of designer piperazines in urine specimens using GC-MS and LC-ESI-MS. CPP has been used to investigate the in vitro efficacy of newly synthesized compounds such as fluoroquinolones (norfloxacine and lomefloxacine) against Philasterides dicentrarchi .

Packaging

5, 25 g in glass bottle

Biochem/physiol Actions

1-(3-Chlorophenyl)piperazine induces hypophagia in food-deprived and freely feeding rats. CPP has affinity for 11 neurotransmitter receptor binding sites in human brain membranes.

5-HT2c serotonin receptor agonist; metabolite of trazodone.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

???PDP_SDS_LOT_NUMBER_ERROR_MSG???

Certificate of Origin

???PDP_SDS_LOT_NUMBER_ERROR_MSG???

Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?