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132888 Sigma-Aldrich

2-Chloro-4′-fluoroacetophenone

99%

Synonym: ω-Chloro-4-fluoroacetophenone, 4-Fluorophenacyl chloride

  • CAS Number 456-04-2

  • Linear Formula FC6H4COCH2Cl

  • Molecular Weight 172.58

  •  Beilstein/REAXYS Number 637860

  •  EC Number 207-256-4

  •  MDL number MFCD00011652

  •  PubChem Substance ID 24848083

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Description

General description

2-Chloro-4′-fluoroacetophenone on condensation with N-methyl-4-(methylthio)benzamidine yields 1-methyl-2-(4-methylthio)phenyl-4-(4-fluoro)phenylimidazole.

Application

2-Chloro-4′-fluoroacetophenone was used in the synthesis of S-(phenacyl)glutathiones and 2-[3-(4-chlorophenyl)-3-hydroxy-8-azabicyclo[3.2.1]oct-8-yl]-1-(4-fluorophenyl)ethanone.

Packaging

25, 100 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 3261 8 / PGII
WGK Germany 
3
RTECS 
AM6550000
Flash Point(F) 
230 °F
Flash Point(C) 
110 °C

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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