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142433 Sigma-Aldrich

Phenylglyoxal hydrate

97%

Synonym: 2,2-Dihydroxyacetophenone

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Properties

Related Categories Aldehydes, Building Blocks, C8, Carbonyl Compounds, Chemical Synthesis,
InChI Key   YQBLQKZERMAVDO-UHFFFAOYSA-N
assay   97%
bp   142 °C/125 mmHg(lit.)
mp   76-79 °C (lit.)
solubility   95% ethanol: soluble 5%, clear to very slightly hazy, colorless to light yellow

Description

Application

Phenylglyoxal hydrate was used :
• to modify pig muscle carbonic anhydraseIII
• as specific reagent for arginine groups
• to prepare pyrrolinone and furan derivatives
• as chemiluminescent reagent for the determination of purines

Packaging

5, 25 g in glass bottle

Biochem/physiol Actions

Phenylglyoxal is a potent inhibitor of mitochondrial aldehyde dehydrogenase. It reacts with arginine residues in purified Hageman factor (HF, Factor XII) and causes inhibition of its coagulant properties.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
KM5775180
Protocols & Articles
Peer-Reviewed Papers
15

References

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