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146064 Sigma-Aldrich

β-Alanine

99%

Synonym: β-Ala, 3-Aminopropionic acid

  • CAS Number 107-95-9

  • Linear Formula NH2CH2CH2COOH

  • Molecular Weight 89.09

  •  Beilstein/REAXYS Number 906793

  •  EC Number 203-536-5

  •  MDL number MFCD00008200

  •  eCl@ss 39030936

  •  PubChem Substance ID 24848760

  •  NACRES NA.26

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Properties

Related Categories Amino Acids, Beta-Amino Acids, Cell Biology, Cell Signaling and Neuroscience, Chemical Biology,
assay   99%
form   powder, crystals or granules
application(s)   ligand binding assay: suitable
  peptide synthesis: suitable
color   white
mp   202 °C (dec.) (lit.)
storage temp.   room temp
SMILES string   NCCC(O)=O
InChI   1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)
InChI key   UCMIRNVEIXFBKS-UHFFFAOYSA-N

Description

Application

β-Alanine has been used as a ligand for the orphan MAS-related receptor. It has also been used in culture media used for certain strains of yeast to test for β-alanine auxotrophy.

Packaging

2 kg in poly bottle

25, 500 g in poly bottle

Biochem/physiol Actions

β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
UA2369200
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

β-Amino Acids and Homologs

Although they are less abundant than their α-analogues, β-amino acids occur in nature both in free form and bound to peptides. Oligomers composed exclusively of β-amino acids (so-called β-peptides) m...
Matthias Junkers
Aldrich ChemFiles 2008, 8.7, 11.
Keywords: Chemfiles, Degradations, Metabolism, Peptidomimetics

Peer-Reviewed Papers
15

References

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