EMAIL THIS PAGE TO A FRIEND
151823 Sigma-Aldrich

Chloroform-d

99.8 atom % D

Synonym: Deuterochloroform

  • CAS Number 865-49-6

  • Linear Formula CDCl3

  • Molecular Weight 120.38

  •  Beilstein/REAXYS Number 1697633

  •  EC Number 212-742-4

  •  MDL number MFCD00000827

  •  PubChem Substance ID 24849167

  •  NACRES NA.21

Purchase

Properties

Related Categories Alphabetical Listings, C, Chloroform, Chloroform-d, Common NMR Solvents,
Quality Level   200
isotopic purity   99.8 atom % D
assay   ≥99% (CP)
form   liquid
application(s)   NMR: suitable
refractive index   n20/D 1.444 (lit.)
bp   60.9 °C (lit.)
mp   −64 °C (lit.)
density   1.500 g/mL at 25 °C (lit.)
mass shift   M+1
SMILES string   [2H]C(Cl)(Cl)Cl
InChI   1S/CHCl3/c2-1(3)4/h1H/i1D
InChI key   HEDRZPFGACZZDS-MICDWDOJSA-N

Description

General description

Chloroform-d (Deuterochloroform, CDCl3), deuterated chloroform, is a standard purity solvent for NMR (Nuclear Magnetic Resonance) analyses. It is widely employed in high resolution NMR studies due to its high chemical and isotopic purity. Quantitaive infrared spectral investigations of carbon-deuterium stretching bands of chloroform-d in various organic solvents have been reported. Raman difference spectroscopic studies of mixtures of chloroform-d and liquid chloroform have been conducted to evaluate frequency shifts in the ν1 and ν2 bands of CHCl3 and CDCl3.

Application

Chloroform-d has been employed as solvent in a 1H NMR (Proton Nuclear Magnetic Resonance) spectroscopic study. It has been employed as solvent during the 31PNMR (Phosphorus-31 nuclear magnetic resonance) spectral investigation of triphenyl phosphate and tris(2-chloroethyl) phosphate. It has also been used as the deuterated solvent in the 1H NMR spectral studies of 2-(4-bromobenzyl)-3-hydroxypropanoic acid and 3-hydroxy-2-(4-methoxybenzyl)propanoic acid. It has also been used as the deuterated solvent for the 1HNMR spectral studies of 3,3′-dihydroxy-4,4′-diamino-biphenyl (HAB) and 2,2′-bis-(3,4-dicarboxy-phenyl) hexafluoropropane dianhydride (6FDA) polyimide.

Packaging

1 kg in glass bottle

10×0.6, 10×0.75, 10×1 mL in ampule

50, 100, 250 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
RIDADR 
UN 1888 6.1 / PGIII
WGK Germany 
WGK 3
Protocols & Articles

Articles

NMR Deuterated Solvent Properties Reference Chart

Use the chart below to look up the coupling values — JHD and JCD(JCF) distance between multiplet peaks in hertz (Hz) — and chemical shift delta values — ðH(Mult)b and ðc(Mult)b in parts per million (...
Keywords: Melting, Nuclear magnetic resonance spectroscopy, Solvents

Pressure-Temperature Calculator for Solvents

*Calculations provide estimated results based on Antoine's Coefficients and their associated temperature range values. Antoine's Coefficients were obtained from the National Institute of Standards an...

Related Content

Pressure-Temperature Nomograph Interactive Tool

Use the interactive controls above to simplify calculations and improve the efficiency of your distillation or evaporation requirements.
Keywords: Evaporation, Vaporization

Properties of Solvents Chart

The solvent property charta lists the physical properties of solvents like Acetone, Benzene and Acetic Acid in alphabetical order for easier referencing. Use the solvent chart in the lab to find comm...
Keywords: Green chemistry, Melting, Solvents

Solvent Miscibility Table

Miscibility defines how substances combine (or mix) to form a homogenous solution without precipitates. Miscibility most often refers to liquids but can also apply to gas and solid phases.
Keywords: Calorimetry, Materials Science, PAGE, Pharmaceutical, Semiconductor, Separation, Solvents, Spectroscopy

Peer-Reviewed Papers
15

References

Related Products

recommended

Product #

Description

Add to Cart

Z271993 Wilmad® NMR tubes 5 mm diam., precision, frequency 300 MHz, L 7 in.

suggested gloves for splash protection

Product #

Description

Add to Cart

Z677698 Vitoject fluorocarbon rubber gloves, size S (8)
Z677701 Vitoject fluorocarbon rubber gloves, size M (9)
Z677728 Vitoject fluorocarbon rubber gloves, size L (10)
Z677736 Vitoject fluorocarbon rubber gloves, size XL (11)

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?