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15420 Sigma-Aldrich

Boc-Gly-OH

≥99.0% (T)

Synonym: N-(tert-Butoxycarbonyl)glycine, Boc-glycine

  • CAS Number 4530-20-5

  • Linear Formula (CH3)3COCONHCH2COOH

  • Molecular Weight 175.18

  •  Beilstein/REAXYS Number 1101514

  •  EC Number 224-864-5

  •  MDL number MFCD00002690

  •  PubChem Substance ID 57647418

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Properties

Related Categories Amino Acids & Derivatives, Chemical Biology, Chemical Synthesis, Glycine, Peptide Synthesis and Peptide Chemistry,
InChI Key   VRPJIFMKZZEXLR-UHFFFAOYSA-N
assay   ≥99.0% (T)
ign. residue   ≤0.05%
mp   86-89 °C (lit.)
  86-89 °C

Description

Application

Boc-Gly-OH can be used:
• For the esterification reaction to synthesize N-Boc amino acid esters for peptide chemistry.
• For the synthesis of tripeptide H-Gly-Pro-Glu-OH, analogs of neuroprotective drugs.
• As a promoter for the allylation of hydrazones and isatin.

Packaging

5, 25, 100 g in glass bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles

Articles

Natural Amino Acid Building Blocks for Peptide Synthesis

With a growing peptide drug market the fast, reliable and uncomplicated synthesis of peptides is of paramount importance.1 Today, the most common synthetic approaches to medium and even large peptide...
Matthias Junkers
ChemFiles 2008, 8.7, 22.
Keywords: Building blocks, Peptide synthesis, Peptidomimetics, Solid phase peptide synthesis

Peer-Reviewed Papers
15

References

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