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155241 Sigma-Aldrich

1-Methyl-2-piperidinemethanol

98%

Synonym: 2-Hydroxymethyl-1-methylpiperidine, NSC 45464

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Properties

Related Categories Building Blocks, C5 to C7, Chemical Synthesis, Heterocyclic Building Blocks, Piperidines More...
assay   98%
refractive index   n20/D 1.4823 (lit.)
bp   79-80 °C/7 mmHg (lit.)
density   0.984 g/mL at 25 °C (lit.)
storage temp.   room temp
SMILES string   CN1CCCCC1CO
InChI   1S/C7H15NO/c1-8-5-3-2-4-7(8)6-9/h7,9H,2-6H2,1H3
InChI key   HXXJMMLIEYAFOZ-UHFFFAOYSA-N

Description

General description

The standard molar energy of combustion of 1-Methyl-2-piperidinemethanol has been studied.

Application

Reactant for synthesis of:
Selective MCH1R antagonists
Human GnRH receptor antagonists
Dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor 1 inhibitors
Radioiodinatable brain imaging agents for CB1 cannabinoid receptor
GABAA receptor agonists at the α3 subunit
Carbamates and N-alkylimidazoles from reaction of carbonyldiimidazoles with alcohols

Packaging

25 g in glass bottle

Safety & Documentation

Safety Information

WGK Germany 
WGK 3
Flash Point(F) 
177.8 °F - closed cup
Flash Point(C) 
81 °C - closed cup
Protocols & Articles
Peer-Reviewed Papers
15

References

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