• USA Home
  • 155268 - (R)-(+)-α-Methoxy-α-trifluoromethylphenylacetic acid

EMAIL THIS PAGE TO A FRIEND
155268 Sigma-Aldrich

(R)-(+)-α-Methoxy-α-trifluoromethylphenylacetic acid

99%

Synonym: (+)-MTPA, Mosher’s acid

  • CAS Number 20445-31-2

  • Linear Formula C6H5C(OCH3)(CF3)CO2H

  • Molecular Weight 234.17

  •  Beilstein/REAXYS Number 3591560

  •  EC Number 243-829-5

  •  MDL number MFCD00004184

  •  PubChem Substance ID 24849508

Purchase

Properties

Related Categories Asymmetric Synthesis, Carboxylic Acids, Chemical Synthesis, Chiral Building Blocks, Chiral Resolution Reagents,
Quality Level   100
assay   99%
optical activity   [α]20/D +72°, c = 1.6 in methanol
optical purity   ee: 99% (GLC)
refractive index   n20/D 1.473 (lit.)
bp   105-107 °C/1 mmHg (lit.)
mp   46-49 °C (lit.)
density   1.344 g/mL at 25 °C (lit.)
storage temp.   2-8°C
SMILES string   CO[C@@](C(O)=O)(c1ccccc1)C(F)(F)F
InChI   1S/C10H9F3O3/c1-16-9(8(14)15,10(11,12)13)7-5-3-2-4-6-7/h2-6H,1H3,(H,14,15)/t9-/m1/s1
InChI key   JJYKJUXBWFATTE-SECBINFHSA-N

Description

Application

(R)-(+)-α-Methoxy-α-trifluoromethylphenylacetic acid is commonly used as a derivatizing agent in Mosher ester analysis, an NMR-based method for determining the absolute configuration of the chiral carbon center in a secondary alcohol.

Packaging

1, 5 g in glass bottle

250 mg in glass bottle

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

doi:10.1038/nprot.2007.354

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
235.4 °F - closed cup
Flash Point(C) 
113 °C - closed cup
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?