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15544 Sigma-Aldrich

Boc-Hyp-OH

≥98.0% (TLC)

Synonym: trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline, Boc-L-hydroxyproline

  • CAS Number 13726-69-7

  • Empirical Formula (Hill Notation) C10H17NO5

  • Molecular Weight 231.25

  •  Beilstein/REAXYS Number 4295484

  •  MDL number MFCD00053370

  •  eCl@ss 32160406

  •  PubChem Substance ID 57647487

  •  NACRES NA.22

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Peptide Synthesis and Peptide Chemistry, Proline Derivatives, Unnatural Amino Acids & Derivatives More...
assay   ≥98.0% (TLC)
optical activity   [α]20/D −53.5±2°, c = 1% in DMF
mp   123-127 °C (lit.)
SMILES string   CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(O)=O
InChI   1S/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7+/m1/s1
InChI key   BENKAPCDIOILGV-RQJHMYQMSA-N

Description

Packaging

5, 25 g in poly bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Proline Derivatives and Analogs

Proline is a non-polar proteinogenic amino acid that forms a tertiary amide when incorporated into peptides. It does not have a hydrogen on the amide group and therefore cannot act as a hydrogen bond...
Chemfiles Volume 5 Article 12
Keywords: Adhesion, Biochemistry, Catalysis, Deposition, Hydroxylations, Isomerizations, Nucleic acid hybridization, Pharmaceutical, Reductions, Substitutions, Type

Proline Derivatives

Proline is a non-polar, natural amino acid that forms a tertiary amide when incorporated into peptides. Thus, it is the only proteinogenic amino acid that does not act as a hydrogen bond donor in a p...
Matthias Junkers
Aldrich ChemFiles 2008, 8.7, 8.
Keywords: Asymmetric synthesis, Chemfiles, Pharmaceutical

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