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159034 Sigma-Aldrich

Acetohydroxamic acid

98%

Synonym: AHA

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Properties

Related Categories Building Blocks, Chemical Synthesis, Hydroxylamines, Nitrogen Compounds - Organic Building Blocks, Organic Building Blocks More...
Quality Level   100
assay   98%
mp   88-90 °C (lit.)
SMILES string   CC(NO)=O
InChI   1S/C2H5NO2/c1-2(4)3-5/h5H,1H3,(H,3,4)
InChI key   RRUDCFGSUDOHDG-UHFFFAOYSA-N
Gene Information   human ... CA2(760), MMP3(4314)

Description

General description

Acetohydroxamic acid is a potent inhibitor of bacterial urease activity and reduces urinary ammonia levels. 2-Acetohydroxamic acid loaded floating microspheres forms an efficient drug delivery system for the treatment of Helicobacter pylori.

Application

Acetohydroxamic acid was used:
• to study the mechanism of complexation of iron (III) with acetohydroxamic acid
• to study the inhibitory mechanism of lansoprazole and omeprazole on Helicobacter pyloni
• in urease inhibition studies
• for in situ generation of nitrosocarbonylmethane as a Diels-Alder dienophile

Used in urease inhibition studies and for in situ generation of nitrosocarbonylmethane as a Diels-Alder dienophile.

Packaging

5, 10, 50 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
AK8157000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Meet Synthia - Retrosynthesis Sofware
Protocols & Articles
Peer-Reviewed Papers
15

References

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