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16490 Sigma-Aldrich

Bromopyruvic acid

≥98.0%

Synonym: 3-Bromo-2-oxopropionic acid

  • CAS Number 1113-59-3

  • Linear Formula BrCH2COCOOH

  • Molecular Weight 166.96

  •  Beilstein/REAXYS Number 1746786

  •  EC Number 214-206-5

  •  MDL number MFCD00002587

  •  PubChem Substance ID 57647568

  •  NACRES NA.22

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Properties

Related Categories Aerobic Glycolysis (the Warburg Effect), Building Blocks, C1 to C5, Cancer Metabolism, Cancer Research,
Quality Level   200
assay   ≥98.0%
mp   77-82 °C
solubility   water: soluble 1 g/10 mL, clear to very slightly hazy, colorless
storage temp.   2-8°C
SMILES string   OC(=O)C(=O)CBr
InChI   1S/C3H3BrO3/c4-1-2(5)3(6)7/h1H2,(H,6,7)
InChI key   PRRZDZJYSJLDBS-UHFFFAOYSA-N

Description

General description

Bromopyruvic acid is an affinity label for cysteine residues†. It acts as cross-linker between nucleic acids and proteins. Kinetics of inactivation of pancreatic ribonuclease A by bromopyruvic acid has been investigated.

may contain traces of dibromopyruvic acid

Application

Bromopyruvic acid was used in the synthesis of imidazo[1,2-a]pyridine-2-carboxylic acids.

Packaging

10, 50, 500 g in glass bottle

Other Notes

Affinity label for cysteine residues; Cross-linker between nucleic acids and proteins

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3261 8 / PGII
WGK Germany 
WGK 3
RTECS 
UZ0840000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Aerobic Glycolysis and the Warburg Effect

The Warburg effect is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer ce...
BioFiles v7 n4
Keywords: Aerobic, Cancer, Cell proliferation, Clinical, Glycolysis, Phosphorylations, Transcription

Peer-Reviewed Papers
15

References

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