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165344 Sigma-Aldrich

1-[3-(Dimethylamino)propyl]-3-ethylcarbodiimide methiodide

Synonym: EDC methiodide

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Properties

Related Categories Carbodiimides, Chemical Biology, Chemical Synthesis, Coupling, Peptide Coupling,
Quality Level   200
application(s)   peptide synthesis: suitable
mp   97-99 °C (lit.)
storage temp.   2-8°C
SMILES string   [I-].CCN=C=NCCC[N+](C)(C)C
InChI   1S/C9H20N3.HI/c1-5-10-9-11-7-6-8-12(2,3)4;/h5-8H2,1-4H3;1H/q+1;/p-1
InChI key   AGSKWMRPXWHSPF-UHFFFAOYSA-M

Description

Application

• Crosslinking agent

Reactant for:
• Amide bond forming (amidation) crosslinking reactions

Water-soluble carboxyl modifying reagent for proteins.

Packaging

1, 10 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Carbodiimides

Carbodiimide-mediated peptide coupling remains to the most frequently used technique. As a major advantage, carbodiimides do not require prior activation of the carboxylic acid. Dicyclohexylcarbodiim...
Matthias Junkers
Aldrich ChemFiles 2007, 7.2, 5.
Keywords: Cyclizations, Peptide synthesis, Solid phase peptide synthesis

Peer-Reviewed Papers
15

References

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