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172405 Sigma-Aldrich

Tetraethylene glycol dimethyl ether

≥99%

Synonym: 2,5,8,11,14-Pentaoxapentadecane, Bis[2-(2-methoxyethoxy)ethyl] ether, Dimethoxytetraethylene glycol, Dimethyltetraglycol, Tetraglyme

  • CAS Number 143-24-8

  • Linear Formula CH3O(CH2CH2O)4CH3

  • Molecular Weight 222.28

  •  Beilstein/REAXYS Number 1760005

  •  EC Number 205-594-7

  •  MDL number MFCD00008505

  •  PubChem Substance ID 24850399

  •  NACRES NA.23

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Properties

Related Categories Alkyl, Biomaterials, Crosslinking Agents, Homobifunctional PEGs, Materials Science,
vapor density   7.7 (vs air)
vapor pressure   <0.01 mmHg ( 20 °C)
assay   ≥99%
  ≥99.0% (GC)
autoignition temp.   510 °F
impurities   ≤1.0% Water (Karl Fischer)
  ≤50 ppm Trace peroxide (as H2O2)
refractive index   n20/D 1.432 (lit.)
bp   275-276 °C (lit.)
mp   −30 °C (lit.)
density   1.009 g/mL at 25 °C (lit.)
polymer architecture   shape : linear
functionality : homobifunctional
reaction suitability   reagent type: cross-linking reagent
reaction type: click chemistry
SMILES string   COCCOCCOCCOCCOC
InChI   1S/C10H22O5/c1-11-3-5-13-7-9-15-10-8-14-6-4-12-2/h3-10H2,1-2H3
InChI key   ZUHZGEOKBKGPSW-UHFFFAOYSA-N

Description

General description

Tetraethylene glycol dimethyl ether or tetraglyme is an organic aprotic colourless solvent with film forming ability.

Application

Tetraglyme coating was applied on glucose sensors, such as Nafion by RF to render it “non fouling” and enhancing linking of bio mimetic molecules to the surface. Tetraglyme helps in selective adsorption of proteins while promoting cell adhesion. Other general uses include as an electrolyte in lithium ion battery.

Packaging

1 kg in glass bottle

250 g in glass bottle

Legal Information

Nafion is a trademark of The Chemours Company FC, LLC

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
SB0400000
Flash Point(F) 
285.8 °F
Flash Point(C) 
141 °C
Protocols & Articles

Articles

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of et...
Keywords: Adhesion, Bacterial conjugations, Click chemistry, Molecular biology, PEGylations, Polymerization reactions, Ring-opening polymerization

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Medical Materials

Medical Device manufacturers partner with us to source quality raw materials, obtain supply chain security, and to leverage a wide range of services to accelerate product development. 
Keywords: Environmental, Microbiology, Pyrogens

Peer-Reviewed Papers
15

References

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