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180947 Sigma-Aldrich

Alginic acid sodium salt


Synonym: Algin, Sodium alginate



General description

Alginic acid sodium is a gelling and nontoxic anionic polysaccharide. The carboxylic acid groups on the alginic acid chain, renders it insoluble in water.However, converting alginic acid to its sodium form, enables it to solubilize in water easily.


Alginic acid sodium is used:
• in combination with chitosan, to fabricate a biodegradable porous scaffold for bone tissue engineering.
• to study the characteristics of a modified amphiphilic alginate derivative
• to the study the impact of alginate on the rate of lipid digestion by employing an in vitro digestion model
• in the preparation of alginate hydrogels
• as encapsulating agents of microparticles of β-galactosidae


100, 250, 500 g in poly bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
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What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
How do I dissolve Product No. 180947, Alginic acid sodium salt?
Product No. 180947, Alginic acid sodium salt, is soluble in water.
What is the molecular weight of Product No. 180947, Alginic acid sodium salt?
The molecular weight of Product No. 180947, Alginic acid sodium salt, is 120,000-190,000 g/moL.
What is the ratio of mannuronic acid to guluronic acid in Product No. 180947, Alginic acid sodium salt?
The ratio of mannuronic acid to guluronic acid (M/G ratio) is 1.56.
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Protocols & Articles


3D Printing of Carbon Fiber-Reinforced Composites

3D printing is a type of additive manufacturing that can be used to rapidly fabricate components with highly customizable geometries, most typically using a layer-by-layer fabrication process. 3D pri...
Zhenyu Bo* (Ph.D Candidate at Northwestern University) and Jia Choi*, PhD, Product Manager

*Materials Science Product Management Team, MilliporeSigma, Milwaukee, WI.
Keywords: Deposition, Nanomaterials, Nanotubes

Chitosan Biopolymer from Fungal Fermentation for Delivery of Chemotherapeutic Agents

David Brown,1 Keith Brunt,2 Nils Rehmann3 1CTO Mycodev Group, Fredericton, NB E3B 6B3 Canada 2Dalhousie School of Medicine New Brunswick, Saint John, NB E2K 5E2, Canada 3NiRem Consulting, 8 Fish Hatc...
David Brown, Keith Brunt, Nils Rehmann
Material Matters, 2016, 11.3
Keywords: Antimicrobials, Bacterial conjugations, Cancer, Click chemistry, Clinical, Fermentation, Hemostatics, Pharmaceutical, Titrations

Injectable Hydrogels for Cell Delivery and Tissue Regeneration

Prathamesh M. Kharkar,1 April M. Kloxin1,2* 1Materials Science and Engineering and 2Chemical and Biomolecular Engineering University of Delaware, Newark, DE 19716 USA *Email: akloxin@udel.edu
Keywords: Addition reactions, Adhesion, Angiogenesis, Biochemistry, Biomaterials, Building blocks, Cardiovascular, Catalysis, Cell proliferation, Click chemistry, Clinical, Cycloadditions, Degradations, Growth factors, Reversed-phase chromatography

Tailoring Collagen-Based Matrices for Regenerative Medicine and Tissue Engineering

Jiayu Leong,1 Liam Grover,2 Hyunjoon Kong1* 1Department of Chemical and Biomolecular Engineering University of Illinois, Urbana-Champaign, IL 61801 USA 2University of Birmingham, UK *Email: hjkong06@...
Keywords: Adhesion, Adsorption, Aminations, Bacterial conjugations, Biomaterials, Building blocks, Cell culture, Clinical, Deaminations, Degradations, Deposition, Diffusion, Growth factors, Hydroxylations, Immobilization, Ligands, Methylations, Michael reaction, PAGE, Purification, Recombination, Reductive aminations, Transfection

Peer-Reviewed Papers


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