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183075 Sigma-Aldrich

1-Methylisatin

97%

Synonym: N-Methylindoline-2,3-dione, NSC 42449

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Properties

Related Categories Building Blocks, C7 to C9, Chemical Synthesis, Heterocyclic Building Blocks, Indoles More...
assay   97%
mp   130-133 °C (lit.)
SMILES string   CN1C(=O)C(=O)c2ccccc12
InChI   1S/C9H7NO2/c1-10-7-5-3-2-4-6(7)8(11)9(10)12/h2-5H,1H3
InChI key   VCYBVWFTGAZHGH-UHFFFAOYSA-N
Gene Information   human ... CASP3(836)

Description

General description

The interaction between 1-methylisatin and human adult haemoglobin was studied using the circular dichroism (CD) spectroscopic, anisotropy and FTIR investigations.

Application

• Reactant for stereoselective preparation of spirobicyclic and bis-spirotricyclic pyrazolidinones
• Reactant for regioselective preparation of spirocyclic oxindole-butenolides
• Reactant for synthesis of spiro-oxindoles
• Reactant for preparation of unsymmetrical oxindoles
• Reactant for stereoselective preparation of hydroxyloxindoles via Morita-Baylis-Hillman reaction
• Reactant for preparation of pyridinecarboxylic acid [(oxo)indolylidene)hydrazide derivatives (Schiff base hydrazides) as antibacterial agents

Packaging

1, 10 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
NL7939000

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Protocols & Articles
Peer-Reviewed Papers
15

References

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