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194719 Sigma-Aldrich

Vincamine

98%

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Properties

Related Categories Alkaloid, Asymmetric Synthesis, Cell Biology, Chemical Synthesis, Chiral Building Blocks,
Quality Level   100
assay   98%
optical activity   [α]23/D +42.8°, c = 1 in pyridine
mp   232 °C (dec.) (lit.)
SMILES string   CC[C@@]12CCCN3CCc4c(C13)n(c5ccccc45)[C@](O)(C2)C(=O)OC
InChI   1S/C21H26N2O3/c1-3-20-10-6-11-22-12-9-15-14-7-4-5-8-16(14)23(17(15)18(20)22)21(25,13-20)19(24)26-2/h4-5,7-8,18,25H,3,6,9-13H2,1-2H3/t18-,20+,21+/m1/s1
InChI key   RXPRRQLKFXBCSJ-GIVPXCGWSA-N

Description

Application

Vincamine can be used as a starting material to synthesize:
•  Vincamine acid, which is employed as a precursor in the synthesis of vinpocetine by dehydration and esterification using sulfuric acid.
•  Apovincamine using iron(III) perchlorate.
•  (-)-Criocerine via one-step iodination reaction.

Packaging

1 g in glass bottle

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
YY8575000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles
Peer-Reviewed Papers
15

References

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