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201634 Sigma-Aldrich

6-Aminofluorescein

Synonym: Fluoresceinamine isomer II

  • CAS Number 51649-83-3

  • Empirical Formula (Hill Notation) C20H13NO5

  • Molecular Weight 347.32

  •  Beilstein/REAXYS Number 51708

  •  EC Number 257-334-7

  •  MDL number MFCD00005051

  •  PubChem Substance ID 24852016

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Properties

Related Categories Biochemicals and Reagents, Derivatization agents, Fluorescent Probes, Labels, Particles and Stains, Functional Group Reactive Labels, Functional Group Reactive Labels for Immunoassays,
InChI Key   YOAWSYSKQHLFPM-UHFFFAOYSA-N
mp   285 °C (dec.) (lit.)
solubility   methanol: 1 mg/mL, clear, yellow to very dark yellow-orange
absorption   λmax 495 nm

Description

Application

6-Aminofluorescein has been demonstrated to be useful fluorescent labeling reagent for fullerene-based liposome nanostructures termed ‘buckysomes’. 6-aminofluorescein dissolved in 0.1 N NaOH can be quantified from a maximum absorbance at 490 nm. Decarboxylated 6-aminofluorescein dissolved 6 N HCl (prepare by constant boiling at 110° C for 24 h) can be quantified from a maximum absorbance at 454 nm. Aldehyde groups are formed by oxidateive damage to proteins, which can be detected by conjugation to decarboxylated 6-aminofluorescein.

6-Aminofluorescein has been used to determine its ability to potentiate the antiviral activity of poly r (A-U).

Packaging

1 g in glass bottle

250 mg in glass insert

Other Notes

Note: Do not confuse with fluorescamine.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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