• USA Home
  • 205249 - Di-tert-butyl dicarbonate

EMAIL THIS PAGE TO A FRIEND
205249 Sigma-Aldrich

Di-tert-butyl dicarbonate

ReagentPlus®, 99%

Synonym: Boc anhydride, Di-tert-butyl pyrocarbonate

  • CAS Number 24424-99-5

  • Linear Formula [(CH3)3COCO]2O

  • Molecular Weight 218.25

  •  Beilstein/REAXYS Number 1911173

  •  EC Number 246-240-1

  •  MDL number MFCD00008805

  •  PubChem Substance ID 24852315

  •  NACRES NA.22

Purchase

Properties

Related Categories Amine Protection, Chemical Biology, Chemical Reagents, Chemical Synthesis, Development Quantities for Research,
Quality Level   200
grade   ReagentPlus®
assay   99%
application(s)   peptide synthesis: suitable
refractive index   n20/D 1.409 (lit.)
bp   56-57 °C/0.5 mmHg (lit.)
mp   23 °C (lit.)
density   0.95 g/mL at 25 °C (lit.)
storage temp.   2-8°C
SMILES string   CC(C)(C)OC(=O)OC(=O)OC(C)(C)C
InChI   1S/C10H18O5/c1-9(2,3)14-7(11)13-8(12)15-10(4,5)6/h1-6H3
InChI key   DYHSDKLCOJIUFX-UHFFFAOYSA-N

Description

Packaging

1 kg in poly bottle

10 kg in composite drum

10, 50, 100 g in poly bottle

Application

Aminomethyl allene was prepared by reaction of Boc propargyl amine with formaldehyde, diisopropylamine and copper bromide as part of a series of Bovine Plasma Amine Oxidase inactivators.

Protection of alcohols as Boc derivatives via Lewis acid catalysis.

Reagent for the introduction of the Boc protecting group.

Reagent for the preparation of Boc protected amines.

Tris-Boc protected hydrazine allows preparation of Fmoc ester in a chromophoric reagent to monitor solid-phase aldehydes.

Warning

Hydrolyzes to t-butanol and CO2; causes internal pressure in bottle if exposed to moisture.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Target organs 
Respiratory system
RIDADR 
UN 2929 3(6.1) / PGII
WGK Germany 
WGK 3
RTECS 
HT0230000
Flash Point(F) 
98.6 °F - closed cup
Flash Point(C) 
37 °C - closed cup
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?