• USA Home
  • 214973 - Diisobutylaluminum hydride solution

EMAIL THIS PAGE TO A FRIEND
214973 Sigma-Aldrich

Diisobutylaluminum hydride solution

1.0 M in methylene chloride

Synonym: DIBAL-H, DIBAL

  • CAS Number 1191-15-7

  • Linear Formula [(CH3)2CHCH2]2AlH

  • Molecular Weight 142.22

  •  Beilstein/REAXYS Number 4123663

  •  MDL number MFCD00008928

  •  eCl@ss 38120609

  •  PubChem Substance ID 24852858

Purchase

Properties

Related Categories Aluminum Hydrides, Chemical Synthesis, Reduction, Synthetic Reagents
InChI Key   AZWXAPCAJCYGIA-UHFFFAOYSA-N
concentration   1.0 M in methylene chloride
density   1.23 g/mL at 25 °C
storage temp.   2-8°C

Description

General description

Diisobutylaluminum hydride is a reducing agent for many functional groups commonly used in organic synthesis.

Application

Diisobutylaluminum hydride solution (1 M in dichloromethane) has been used in the conversion of esters into α-fluoro-α,β-unsaturated esters in the presence of fluorocarboalkoxy-substituted dialkyl phosphonate anions via Horner-Wadsworth-Emmons reaction. It can be used in the multi-step synthesis of (S)-2-methyl tetrahydropyridine-N-oxide, a key structural moiety of bio-active compounds like himbacine and solenopsin-A.

Used in Pd-catalyzed reductive debromination of secondary alkyl bromides. O-Debenzylation and ring opening of perbenzylated furanosides. Convenient in situ generation of HZrCp2Cl from ZrCp2Cl2 and DIBAL-H.

Packaging

1 L in Sure/Seal™

100, 800 mL in Sure/Seal™

Safety & Documentation

Safety Information

Signal word 
Danger
Precautionary statements 
Target organs 
Blood, Central nervous system, Liver
RIDADR 
UN 3394 4.3(4.2) / PGI
WGK Germany 
2
Flash Point(F) 
1.4 °F
Flash Point(C) 
-17 °C

Documents

Certificate of Analysis

???PDP_SDS_LOT_NUMBER_ERROR_MSG???

Certificate of Origin

???PDP_SDS_LOT_NUMBER_ERROR_MSG???
Protocols & Articles

Related Content

Agriculture | Crop Protection Workflow

Pesticides are an essential component in modern agriculture and enable growers to fully realize the yield potential of their seeds. From compound discovery to active ingredient development, our chemi...
Keywords: Agriculture, Building blocks, Gas chromatography, Gas chromatography mass spectrometry, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Organic synthesis, Pesticides, Polymerase chain reaction - quantitative, Purification, Solvents

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?